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Tofranil (Imipramine) is several drugs called tricyclic antidepressants. Imipramine affects chemicals within the brain which could become unbalanced.
It is employed to deal with signs of depression.
This medicine doubles for purposes apart from those placed in this medication guide.


Take prescription drugs exactly as it had been prescribed to suit your needs. Do not take the medication in larger amounts, or go on it for over recommended through your doctor. Your doctor may occasionally make positive changes to dose to successfully obtain the best is a result of this medication. Follow the directions on the prescription label.
If you might want any kind of surgery, tell the surgeon in advance that you are taking imipramine. You may need to stop while using the medicine for a small amount of time.
Do not stop using imipramine without first talking to a medical expert. You may need to use less and less before you decide to stop the medication completely. Stopping prescription drugs suddenly might lead to one to have unpleasant negative effects. It may take as much as 25 days of employing this medicine before your symptoms improve. For best results, keep while using the medication as directed. Talk with your doctor should your symptoms don't improve after 3 weeks of treatment.

If you missed the dose go as soon as you remember. If it really is almost time for your next dose, skip the missed dose and go ahead and take medicine at the next regularly scheduled time. Do not take extra medicine to make the missed dose.

Seek emergency medical help if you think you've got used which is not this medicine. An overdose of imipramine can be fatal.
Symptoms of an imipramine overdose can sometimes include uneven heartbeats, extreme drowsiness, agitation, vomiting, blurred vision, sweating, muscle stiffness, swelling, breathlessness, blue lips or fingernails, feeling light-headed, fainting, seizure (convulsions), or coma.


Take this medicine as prescribed from your doctor.


Store imipramine at room temperature faraway from moisture and warmth.


Active Ingredient: Imipramine

Tofranil is really a tricyclic antidepressant. It works by helping the activity of certain chemicals in the brain which help elevate mood.

Side Effects

Get emergency medical help if you've all of these signs of your allergic reaction: hives; breathlessness; swelling of your respective face, lips, tongue, or throat.

Call your medical professional simultaneously if you might have any new or worsening symptoms like: mood or behavior changes, anxiety, panic and anxiety attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call a medical expert at the same time if you have any of these serious unwanted side effects:

fast, pounding, or uneven heartrate;

chest pain or heavy feeling, pain spreading for the arm or shoulder, nausea, sweating, general ill feeling;

sudden numbness or weakness, especially on the one hand with the body;

sudden headache, confusion, difficulties with vision, speech, or balance;

feeling in short supply of breath, despite mild exertion;

swelling, rapid weight gain;

confusion, hallucinations, or seizure (convulsions);

easy bruising or bleeding, unusual weakness;

restless muscle movements with your eyes, tongue, jaw, or neck;

urinating more or less than usual;

extreme thirst with headache, nausea, vomiting, and weakness;

skin rash, bruising, severe tingling, numbness, pain, or muscle weakness.

Less serious negative effects may be more likely to occur, like:

nausea, vomiting, stomach pain, loss in appetite;

constipation or diarrhea;

dry mouth, unpleasant taste;

weight changes;

weakness, lack of coordination;

feeling dizzy, drowsy, or tired;


blurred vision, headache, ringing with your ears;

breast swelling (in men or women); or

decreased sex drive, impotence, or difficulty owning an orgasm.

Tofranil shall be used only through the patient for whom it can be prescribed. Do not share it with others.
If your symptoms don't improve or if they become worse, consult your physician.


Do not use Tofranil if:

you might be allergic to your ingredient in Tofranil;

you might have taken furazolidone or perhaps a monoamine oxidase inhibitor (MAOI) (e.g., phenelzine) within the past two weeks, or if you take astemizole, droperidol, or terfenadine.

you might be dealing with a recently available cardiac event.
Contact your medical professional or health care provider immediately if any of these apply to you.

Some medical ailments may interact with Tofranil . Tell your medical professional or pharmacist if you might have any medical ailments, particularly when any in the following sign up for you:

if you are pregnant, intending to conceive, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you've allergies to medicines, foods, or another substances

if you drink alcohol-containing beverages daily or you've a history of alcohol abuse

if you adopt thyroid medicine or you've a reputation overactive thyroid, glaucoma, heart problems, kidney or liver problems, diabetes, seizures, the blood disease porphyria, or difficulty urinating

if you might have a good suicidal thoughts or behavior, bipolar disorder, or another mental disorders; you're undergoing electroshock therapy; or you're scheduled to have any surgery.

Some MEDICINES MAY INTERACT with Tofranil . Tell your health care provider if you adopt every other medicines, especially any with the following:

Azole antifungals (eg, fluconazole), cimetidine, duloxetine, flecainide, methylphenidate, mibefradil, phenothiazines (eg, chlorpromazine), propafenone, quinidine, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), or terbinafine because they could raise the likelihood of Tofranil 's side effects

Arsenic, astemizole, droperidol, furazolidone, MAOIs (eg, phenelzine), pimozide, streptogramins (eg, dalfopristin), terfenadine, or tramadol since the risk of blood pressure, serious cardiovascular disease (eg, irregular heartbeat), or seizures could be increased

Barbiturates (eg, phenobarbital) or phenytoin because they may decrease Tofranil 's effectiveness

Anticholinergics (eg, benztropine), carbamazepine, or sympathomimetics (eg, phenylephrine) for the reason that probability of their side effects could possibly be increased by Tofranil

Clonidine, guanethidine, or guanfacine as their effectiveness could be decreased by Tofranil

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