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Precautions

Do NOT use Celebrex if:

• you are allergic to any ingredient in Celebrex
• you experienced an extreme allergic reaction (eg, severe rash, hives, trouble breathing, growths inside nose, dizziness) to aspirin, an NSAID (eg, ibuprofen), or a sulfonamide (eg, sulfamethoxazole)
• you've got recently had or will likely be having heart bypass surgery
• you've severe liver or kidney problems
• you are within the last three months of being pregnant
• you are taking another nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen)

Contact your physician or health care provider without delay if some of these connect with you.

Some medical conditions may connect to Celebrex. Tell a medical expert or pharmacist when you have any health concerns, particularly when any from the following sign up for you:

• if you happen to be pregnant, likely to conceive, or are breast-feeding
• if you consider any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or another substances
• when you have a good reputation for kidney or liver disease, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers)
• in case you have a reputation swelling or fluid buildup, asthma, growths inside nose (nasal polyps), or mouth inflammation
• for those who have a high fever, rash, high blood pressure, blood disorders, bleeding or clotting problems, cardiovascular disease (eg, cardiovascular disease, heart failure), or blood vessel disease, or you might be at risk for some of these diseases
• for those who have poor health, dehydration or low fluid volume, or low blood sodium levels, you drink alcohol or smoke, or you've got a good reputation for irresponsible drinking.

Some medicines may connect to Celebrex. Tell your doctor if you take any other medicines, especially any of the following:

• Anticoagulants (eg, warfarin), aspirin, corticosteroids (eg, prednisone), heparin, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because risk of stomach bleeding might be increased
• Fluconazole, another nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen), or probenecid simply because they may increase the chance of Celebrex's unwanted effects
• Cyclosporine, lithium, methotrexate, or quinolones (eg, ciprofloxacin) because the chance of their unwanted side effects may be increased by Celebrex
• Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin II receptor blockers (eg, valsartan), or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness could possibly be decreased by Celebrex.

This might not exactly be a total listing of all interactions that may occur. Ask your health care provider if Celebrex may talk with other medicines that you take. Check with your health care provider prior to starting, stop, or alter the dose of the medicine.

Important safety information:

• Celebrex may cause dizziness or drowsiness. These effects may be worse if you get it with alcohol or certain medicines. Use Celebrex with caution. Do not drive or perform other possible unsafe tasks unless you recognize how you answer it.
• Serious stomach ulcers or bleeding can occur with the use of Celebrex. Taking it in high doses and for a very long time, smoking, or having a drink increases the risk of these side effects. Taking Celebrex with food will NOT reduce potential risk of these effects. Contact your physician or emergency room immediately for those who have severe stomach or lower back pain; black, tarry stools; vomit that appears like blood or coffee grounds; or unusual fat gain or swelling.
• Do NOT take a lot more than the recommended dose or use more than prescribed without checking with your medical professional
• Celebrex is definitely an NSAID. Before you start any new medicine, look at the label to see whether it has an NSAID (eg, ibuprofen) in it too. If it does or if you happen to be not sure, check with your medical professional or pharmacist.
• Do not take aspirin while you happen to be using Celebrex unless a medical expert informs you to.
• FAP patients - Celebrex will not be shown to reduce FAP-related cancers or perhaps the dependence on other procedures or surgeries. Continue your usual care whilst you use Celebrex.
• Lab tests, including kidney and liver function, complete blood cell counts, blood clotting, and blood pressure levels, could possibly be performed while you use Celebrex. These tests might be used to monitor your condition or pay attention to unwanted effects. Be sure to keep all doctor and lab appointments.
• Use Celebrex with caution within the elderly; they might be more understanding of its effects, especially stomach bleeding and kidney problems.
• Caution is recommended when using Celebrex in kids who've juvenile rheumatism; they could be more understanding of its effects, especially blood clotting problems.
• Pregnancy and breast-feeding: Celebrex might cause injury to the fetus. Do not use it during the final 3 months of being pregnant. If you think you could possibly be pregnant, contact your physician. You will need to discuss the huge benefits and perils associated with using Celebrex while you are pregnant. Celebrex can be found in breast milk. If you're or will likely be breast-feeding whilst you use Celebrex, talk with your doctor. Discuss any possible risks in your baby.