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Eldepryl is indicated being an adjunct inside treatments for Parkinsonian patients being treated with levodopa/carbidopa who exhibit deterioration in the quality of the response to this therapy.


Take this medicine only as directed from your doctor. Do not take more of it, do not take on it more regularly, and do not take on it a bit longer than a medical expert ordered.

It is most beneficial to consider this medicine before breakfast and without liquids.

If you're with all the disintegrating tablet, be sure the hands are dry before you handle today. Do not open the blister pack made up of the tablet until you happen to be ready to go on it. Remove these days in the blister pack by peeling back the foil, then taking the tablet out. Do not push today from the foil. Do not break or split these days. Place today about the top of your tongue, where it'll melt quickly. Do not eat food or drink liquids for 5 minutes before or after taking this medicine.

If you miss a dose of the medicine, go at the earliest opportunity. However, if it is almost time for your forthcoming dose, skip the missed dose and return to your regular dosing schedule. Do not double doses.


The dose of the medicine changes for several patients. Follow your medical professional's orders or even the directions about the label. The following information includes exactly the average doses of the medicine. If your dose is unique, usually do not change it unless your medical professional notifys you for this.

The quantity of medicine that you take depends around the strength from the medicine. Also, the volume of doses you're taking every day, the time allowed between doses, as well as the time period you adopt the medicine depend around the problem for which you happen to be using the medicine.
For oral dosage form (tablets):
For Parkinson's disease:


Store the medicine inside a closed container at room temperature, from heat, moisture, and direct light. Keep from freezing.
Keep out of your reach of children.
Do not keep outdated medicine or medicine will no longer needed.


Eldepryl is a levorotatory acetylenic derivative of phenethylamine. It is commonly described within the clinical and pharmacological literature as l-deprenyl.

Side Effects

Along with its needed effects, a medicine may cause some negative effects. Although not most of these unwanted side effects may occur, whenever they do occur they may need medical assistance.

Check with your medical professional immediately if these things unwanted side effects occur:

More common
Chest pain (severe)
enlarged pupils
fast or slow heartbeat
headache (severe)
increase in unusual movements in the body
increased sensitivity of the eyes to light
increased sweating (possibly with fever or cold, clammy skin)
mood or another mental changes
nausea and vomiting (severe)
stiff or sore neck

Less common or rare
Bloody or black, tarry stools
convulsions (seizures)
decreased urine
difficult or frequent urination
difficulty with breathing
difficulty with speaking
difficulty with swallowing
dizziness or lightheadedness, particularly if getting up coming from a lying or sitting position
dry mouth
hallucinations (seeing, hearing, or feeling items that aren't there)
increased thirst
irregular heartbeat
large, flat, blue, or purplish patches inside skin
lip smacking or puckering
loss of appetite
loss of balance control
muscle pain or cramps
nausea or vomiting
numbness or tingling inside hands, feet, or lips
puffing from the cheeks
rapid or worm-like movements in the tongue
restlessness or desire to keep moving
severe stomach pain
shakiness in the legs, arms, hands, or feet
shortness of breath
swelling in the feet or lower legs
swelling or inflammation from the mouth
tightness within the chest
trembling or shaking from the hands or feet
twisting movements with the body
uncontrolled chewing movements
uncontrolled movements in the face, neck, back, arms, or legs
unusual tiredness or weakness
vomiting of blood or material that appears like coffee grounds

Get emergency help immediately if these things symptoms of overdose occur:

Symptoms of overdose
Agitation or irritability
chest pain
difficulty opening the mouth or lockjaw
dizziness (severe) or fainting
fast or irregular pulse (continuing)
high fever
high or low hypertension
severe spasm where the head and heels are bent backward and the body arched forward
troubled breathing

Some unwanted side effects may occur that always do not need medical assistance. These unwanted effects might have to go away during treatment since your body adjusts for the medicine. Also, your wellbeing care professional may be able to let you know about methods to prevent or reduce a few of these side effects. Check using your health care professional if these things negative effects continue or are bothersome or if you've questions about them:

More common
Abdominal or stomach pain
dizziness or feeling faint
runny nose
stuffy nose
trouble with sleeping

Less common or rare
back or leg pain
blurred or double vision
body aches or pain
burning in the lips, mouth, or throat
dryness or soreness from the throat
frequent urge to urinate
inability to move
increased sweating
irritability (temporary)
memory problems
pounding or fast heartbeat
red, raised, or itchy skin
ringing or buzzing inside the ears
slow or difficult urination
slowed movements
taste changes
uncontrolled closing in the eyelids
unusual a sense well-being
unusual weight loss
voice changes

Other unwanted effects not listed may also occur in some patients. If you notice some other effects, check with your healthcare professional.


It is vital that your medical professional look at the progress at regular visits to allow for changes in your dose and to check for any unwanted effects.

Do not take selegiline if you have used meperidine (e.g., Demerol®) or even an MAO inhibitor (MAOI) (e.g., isocarboxazid, phenelzine, tranylcypromine, Marplan®, Nardil®, or Parnate®) within the past 14 days. If you do, you could develop agitation, confusion, restlessness, stomach or intestinal symptoms, sudden high temperature, elevated hypertension, or severe convulsions.

Do not take cough medicines (e.g., dextromethorphan, Robitussin®, Pediacare®) or pain medicines (e.g., methadone, propoxyphene, tramadol, Darvon®, Dolophine®, Ultram®) while you are employing this medicine. Using these medicines together could cause uncomfortable side effects.

Selegiline could cause serious negative effects when used as well as some antidepressants. Tell your doctor if you've used amitriptyline, doxepin, fluoxetine, fluvoxamine, nortriptyline, paroxetine, sertraline, Elavil®, Luvox®, Pamelor®, Paxil®, Prozac®, or Zoloft® within the past two weeks.

When selegiline is taken at doses of 10 mg or less per day for your treatment of Parkinson's disease, there won't be any restrictions on food or beverages you consume or drink. However, the opportunity exists that dangerous reactions, for example sudden high blood pressure, may occur if doses higher than those used for Parkinson's disease are taken with foods, beverages, or another medicines. These foods, beverages, and medicines include:

Also, for around 2 weeks after you stop investing in this medicine, simply because, beverages, and also other medicines may continue to react with selegiline if it was consumed doses more than those usually useful for Parkinson's disease.

Check with your medical professional or hospital er immediately if severe headache, stiff neck, chest pains, fast heartbeat, or nausea and vomiting occur while you happen to be taking this medicine. These may be the signs of a serious complication which should have a very doctor's attention.

Dizziness, lightheadedness, or fainting may occur, particularly when you receive up from your lying or sitting position. Getting up slowly may help. If the problem continues or gets worse, talk with a medical expert.

Selegiline could cause dryness from the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice inside your mouth, or utilize a saliva substitute. However, should your mouth is constantly feel dry for over two weeks, check along with your medical doctor or dentist. Continuing dryness with the mouth may increase the chance of dental disease, including cavities, gum disease, and fungus infections.

It is essential that your doctor check your skin for melanoma (tumor) regularly if you have Parkinson's disease.

Do not stop using this medicine without first checking with your doctor. Your doctor might want you to reduce gradually the amount you're taking before stopping completely.

Hallucinations may happen in some patients. This is more prevalent with elderly patients. If you might have hallucinations, check with your medical professional.

Some folks who suffer from used this medicine had unusual alterations in their behavior. Talk with your medical professional should you start having issues with gambling or increased libido while by using this medicine.

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