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Precautions

Do NOT use Estrace if:

• you are allergic to any ingredient in Estrace
• you are pregnant or suspect you could be pregnant, have recently given birth or are breast-feeding, or have vaginal bleeding of abnormal or unknown cause
• you might have known or suspected breast cancers (unless directed because of your doctor) or you have cancers which can be estrogen-dependent
• you've got blood clots, vein inflammation, or liver disease
• you also have a recent stroke or heart attack.

Contact your doctor or physician straight away if all of these affect you.

Some medical ailments may talk with Estrace. Tell your physician or pharmacist if you have any medical conditions, in particular when any of the following affect you:

• if you're planning to become pregnant
• if you adopt any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• for those who have allergies to medicines, foods, or other substances
• for those who have a genealogy and family history of breast cancers, otherwise you have breast lumps or disease, or an abnormal mammogram
• when you have yellowing from the whites of the eyes or skin in pregnancy or with past estrogen use, or high blood pressure levels during pregnancy (toxemia)
• in case you have a vaginal infection or womb problems (eg, uterine fibroids/endometriosis, abnormal vaginal bleeding, other uterine problems)
• for those who have abnormal calcium levels within the blood, asthma, cancer, certain blood disorder (porphyria), cholesterol or lipid problems, depression, diabetes, epilepsy, excessive extra weight, gallbladder disease, heart problems or other cardiovascular disease, hypertension, kidney or liver disease, low thyroid hormone levels, lupus, migraine headaches, pancreas disease, seizures, or yellowing from the skin or eyes
• should you smoke or will likely be having surgery.

Some medicines may interact with Estrace. Tell your medical provider if you take any other medicines, especially any with the following:

• Blood thinners (eg, warfarin), corticosteroids (eg, prednisone), succinylcholine, or tacrine as their actions and also the probability of their unwanted effects could be increased by Estrace
• Blood thinners (eg, warfarin) as their effectiveness might be decreased by Estrace
• Barbiturates (eg, phenobarbital), hydantoins (eg, phenytoin), or rifampin simply because they may decrease Estrace's effectiveness.

This will not be a total listing of all interactions that may occur. Ask your doctor if Estrace may talk with other medicines that you just take. Check with your medical provider prior to starting, stop, or customize the dose from a medicine.

Important safety information:

• Estrace could cause dizziness. This effect could be worse should you go with alcohol or certain medicines. Use Estrace with caution. Do not drive or perform other possible unsafe tasks before you understand how you answer it.
• Limit alcoholic beverages when you are taking Estrace.
• Estrace may cause dark skin patches in your face (melasma). Exposure on the sun might make these patches darker and you may have to avoid prolonged sun exposure and sunlamps. Consult your doctor concerning the use of sunscreens and protective clothing.
• Estrace might increase the probability of blood clots. The risk may be greater should you smoke (particularly in women older than 35 years of age).
• Contact a medical expert if vaginal bleeding of unknown cause occurs. This could be a sign of a significant condition requiring immediate medical assistance.
• Contact your physician if vaginal discomfort occurs or if you suspect you've got developed disease while taking Estrace.
• Follow your doctor's instructions for examining your breasts and report any lumps immediately.
• Additional monitoring of your respective dose or condition may be necessary if you are presently taking an azole antifungal (eg, itraconazole), carbamazepine, a macrolide antibiotic (eg, erythromycin), ritonavir, cimetidine, or St. John's wort.
• If you wear contact lenses and also you develop issues with them, get hold of your doctor.
• If you is going to be having surgery or will be limited to a chair or bed for long periods of energy (eg, a long plane flight), notify your physician beforehand. Special precautions may must be used in these circumstances while you're taking Estrace.
• Nonprescription therapy to help you prevent bone loss incorporates a weight-bearing fitness program, in addition to adequate daily calcium and vitamin D intake. Consult a medical expert or pharmacist for more details.
• Some of these products could have the dye tartrazine (FD&C Yellow No. 5), which may cause allergies using patients. Consult a medical expert or pharmacist. If you previously had allergies to the dye tartrazine, get hold of your doctor or pharmacist to find out when the product you are taking contains the dye tartrazine.
• Estrace may obstruct certain tests. Be sure a medical expert and lab personnel know you adopt Estrace.
• Diabetes patients - Estrace may affect your blood glucose levels. Check blood sugar levels closely. Ask a medical expert before you decide to affect the dose of your respective diabetes medicine.
• Lab tests, including physical exams and blood pressure, could possibly be performed as you use Estrace. You should have breast and pelvic exams, and a Pap test at least once per year. You should also have periodic mammograms as determined because of your doctor. Be sure to keep all doctor and lab appointments.
• Estrace shouldn't be employed in children; safety and effectiveness in children have not been confirmed.
• Pregnancy and breast-feeding: Do not use Estrace if you're pregnant. Avoid pregnancy while you are taking it. If you think you could be pregnant, contact your doctor immediately. Estrace could possibly be within breast milk. If you are or will likely be breast-feeding as you use Estrace, check with your doctor. Discuss any possible risks for your baby.