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Precautions

Do NOT use Plendil if:

• you might be allergic to any ingredient in Plendil
• you have a very good reputation for low blood pressure.

Contact a medical expert or health care provider straight away if these apply to you.

Some health concerns may communicate with Plendil. Tell your physician or pharmacist if you have any medical ailments, in particular when any with the following connect with you:

• if you happen to be pregnant, likely to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• when you have allergies to medicines, foods, or other substances
• if you have heart disease, breathing problems, or even a slow heartbeat.

Some medicines may connect to Plendil. Tell your medical provider if you might be taking another medicines, especially any of the following:

• Barbiturates (eg, phenobarbital), carbamazepine, or hydantoins (eg, phenytoin) for the reason that effectiveness of Plendil could be decreased
• Azole antifungals (eg, ketoconazole), cimetidine, or erythromycin as the actions and unwanted effects of Plendil may be increased
• Macrolide immunosuppressives (eg, tacrolimus) for the reason that actions and unwanted side effects of the medicines might be increased.

This might not be an entire list of all interactions that will occur. Ask your doctor if Plendil may interact with other medicines that you take. Check with your doctor before you begin, stop, or affect the dose associated with a medicine.

Important safety information:

• Plendil could potentially cause dizziness or lightheadedness. Do not drive, operate machinery, or a single thing else that could be dangerous until you know how you reply to Plendil. Using Plendil alone, to medicines, or with alcohol may lessen you skill they are driving or to execute other very dangerous tasks.
• Plendil could cause dizziness, lightheadedness, or fainting. Alcohol, warm weather, exercise, and fever can increase these effects. To prevent them, sit or fully stand up slowly, especially within the morning. Also, sit or lay down in the first sign of dizziness, lightheadedness, or weakness.
• Patients receiving care for high blood pressure often feel tired or shabby for a couple weeks after beginning treatment. Continue taking your medication even if you may not feel quite "normal." Contact your doctor or pharmacist about any new symptoms.
• While you might be using Plendil, brush and floss your teeth carefully. Also, have regular dental checkups.
• Use Plendil with extreme caution in children; safety and effectiveness are not confirmed.
• Pregnancy and breast-feeding: If you plan on becoming pregnant, discuss with your doctor the huge benefits and perils of using Plendil while pregnant. It is unknown if this drug is excreted in breast milk. Do not breastfeed while taking Plendil.