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Precautions

Do NOT use Zestoretic if:

• you might be allergic to your ingredient in Zestoretic or some other sulfonamide medicine (eg, sulfamethoxazole, glyburide, probenecid)
• you have a very good angioedema (swelling from the face, lips, throat, or tongue)
• you have a good kidney artery narrowing
• you are unable to urinate
• you are taking dofetilide or ketanserin
• you are pregnant.

Contact your physician or doctor immediately if any of these sign up for you.

Some medical conditions may talk with Zestoretic. Tell a medical expert or pharmacist for those who have any medical conditions, particularly when any with the following apply to you:

• if you're pregnant, about to become pregnant, or are breast-feeding
• should you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• in case you have allergies to medicines, foods, or other substances
• if you might be able to become pregnant
• if you have impaired liver function, blood vessel problems (eg, stroke), heart problems (eg, congestive heart failure), or high cholesterol
• in the event you use a good kidney artery narrowing or decreased kidney function, you're on dialysis, or you've got had a kidney transplant
• in case you have gout, diabetes, or electrolyte imbalances (eg, high or low potassium levels, low blood sodium levels), or you happen to be with a sodium-restricted diet
• in case you possess a collagen vascular disorder (eg, lupus, scleroderma), bone marrow problems, or severe body's defence mechanism problems
• in the event you have a good allergies or asthma
• if you might be scheduled to possess major surgery or receive anesthesia.

Some medicines may interact with Zestoretic. Tell your doctor in the event you consider some other medicines, especially any of the following:

• Aldosterone blockers (eg, eplerenone), corticosteroids (eg, prednisone), digoxin, dofetilide, ketanserin, lithium, loop diuretics (eg, furosemide), potassium preparations, potassium-sparing diuretics (eg, triameterene), or trimethoprim because the chance of electrolyte problems and irregular heartbeat may be increased
• Barbiturates (eg, phenobarbital), dextran sulfate, diazoxide, or narcotic pain medicine (eg, codeine) because the likelihood of low blood pressure levels might be increased
• Gold-containing medicines (eg, sodium aurothiomalate) because flushing, nausea, vomiting, and low blood pressure may occur
• Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, indomethacin, celecoxib) or salicylates (eg, aspirin) given that they may decrease Zestoretic's effectiveness
• Insulin, sulfonylureas (eg, glyburide), or other medicines for diabetes (eg, metformin) because their effectiveness could be decreased by Zestoretic.

This will not be a whole set of all interactions which could occur. Ask your medical provider if Zestoretic may talk with other medicines that you are taking. Check with your health care provider before starting, stop, or change the dose associated with a medicine.

Important safety information:

• Zestoretic could potentially cause dizziness, lightheadedness, or fainting. These effects could be worse if you take it with alcohol or certain medicines. Use Zestoretic with caution. Do not drive or perform other possible unsafe tasks until you discover how you react for it.
• Zestoretic may cause dizziness, lightheadedness, or fainting; alcohol, summer, exercise, or fever may increase these effects. To prevent them, crunch or stand slowly, especially inside morning. Sit or lay down at the first sign of the of these effects.
• Check together with your doctor when you use a salt substitute or a merchandise that has potassium inside it.
• Drink a lot of fluids while taking Zestoretic and prevent starting activities that create sweating. Dehydration, hyperhidrosis, vomiting, or diarrhea can lead to a fall in blood pressure level. Contact your doctor simultaneously if some of these occur.
• Diabetes patients - Zestoretic may raise your blood glucose. High blood glucose might make you are feeling confused, drowsy, or thirsty. It can also allow you to flush, breathe faster, or possess a fruit-like breath odor. If these symptoms occur, tell your physician right away.
• A persistent, unproductive cough may occur. Tell your medical professional if it occurs. Recovery is rapid once the medicine is stopped.
• Patients who take medicine for high blood pressure often feel tired or shabby for a few weeks after starting treatment. Be sure to take your medicine although you may may well not feel "normal." Tell your physician in case you develop any new symptoms.
• Zestoretic might not are well in black patients. They may be also at greater chance of unwanted side effects. Contact your doctor if your symptoms don't improve or if they become worse.
• Tell your physician or dentist that you are taking Zestoretic before you decide to get any medical or dental treatments, emergency care, or surgery.
• Zestoretic could cause you to become sunburned with less effort. Avoid the sun, sunlamps, or tanning booths until you understand how you reply to Zestoretic. Use a sunscreen or wear protective clothing should you must be outside for more than a short period of time.
• Zestoretic may restrict certain lab tests, including parathyroid function tests. Be sure your doctor and lab personnel know you are taking Zestoretic.
• Lab tests, including blood electrolytes, blood pressure levels, complete blood cell counts, and kidney function, could possibly be performed when you use Zestoretic. These tests might be used to monitor your condition or check for unwanted effects. Be sure to keep all doctor and lab appointments.
• Use Zestoretic with caution in the elderly; they may be more responsive to its effects.
• Zestoretic should be used with extreme caution in children; safety and effectiveness in kids have not been confirmed.
• Pregnancy and breast-feeding: Zestoretic could potentially cause birth defects or fetal death if you take it while you happen to be pregnant. If you think you could be pregnant, contact your doctor right away. Zestoretic is found in breast milk. Do not breastfeed while taking Zestoretic.