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Precautions

Do NOT use Coumadin if:

• you are allergic to any ingredient in Coumadin
• you have bleeding tendencies, bleeding problems (eg, hemophilia), severe or uncontrolled high blood pressure, certain blood problems (eg, low white blood cell or platelet levels), or leukemia
• you've got active serious bleeding, bleeding inside brain, certain blood vessel problems (eg, aneurysm, dissecting aorta), or inflammation or infection in the heart
• you've active ulcer or bleeding with the stomach or bowel, urinary tract, genitals, or respiratory tract
• you've recently had or will probably be having eye, brain, or vertebrae surgery; spinal puncture; spinal anesthesia; or any type of major surgery
• you are pregnant or may become pregnant
• you cannot have routine blood clotting tests
• you cannot follow a medical expert's instructions properly and never have someone that may help you take your medicine
• you are taking mifepristone, streptokinase, or urokinase.

Contact your medical professional or health care provider immediately if these connect with you.

Some medical ailments may connect to Coumadin. Tell your physician or pharmacist for those who have any medical conditions, particularly when any from the following apply to you:

• should you be planning to get pregnant or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• in case you have allergies to medicines and other substances
• when you have also been injured, fallen, given birth, or had surgery
• for those who have a reputation stomach or irregularity (eg, bleeding, ulcer, inflammation), cardiovascular disease (eg, heart failure, infection), blood clots, anemia or another blood problems (eg, protein C deficiency, high red blood cell levels), circulation system problems, or hypertension
• if you have a history of liver, kidney, or thyroid problems; yellowing in the skin or eyes; mental or mood problems; high cholesterol; arthritis; diabetes; or cancer
• when you have poor nutrition, celiac disease, nutrient or fat absorption problems, or 'abnormal' amounts of vitamin K or vitamin C inside blood, or in case you are drinking alcohol
• if you have a fever, very poor health, diarrhea, fluid buildup, extra fat inside the stools (steatorrhea), a recent or current infection, or tuberculosis, or should you will probably be exposed to high temperatures to get a prolonged period of time
• if you have a heart valve replacement, an intrauterine device (IUD), or a catheter.

Some medicines may interact with Coumadin. Tell your health care provider if you are taking every other medicines, especially any of the following:

• Heparin or another anticoagulants, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), salicylates (eg, aspirin), streptokinase, or urokinase as the chance of bleeding could possibly be increased
• Mifepristone because excessive bleeding may occur
• Many prescription and nonprescription medicines (eg, used for infections, inflammation, discomfort, hypertension, high cholesterol, seizures, mental or mood problems, diabetes, stomach or bowel obstruction, irregular heartbeat, contraceptive, hormone replacement, cancer, yet others), multivitamin products, and herbal or health supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo, St. John's wort) may interact with Coumadin, helping the chance of serious unwanted effects including bleeding or blood clots.

This may not be a complete listing of all interactions that could occur. Ask your doctor if Coumadin may talk with other medicines that you take. Check with your health care provider before you start, stop, or customize the dose from a medicine.

Important safety information:

• Tell your physician or dentist that you just take Coumadin when you receive any medical or dentistry, emergency care, or surgery.
• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your physician. Contact your doctor right away if you could have taken too much of Coumadin.
• Do not are drinking alcohol when you consider Coumadin; it may well increase the risk of Coumadin's side effects.
• Do not change you activity level or weight without checking with a medical expert; the probability of Coumadin's negative effects could be increased.
• Do not change your diet plan without checking with your medical professional. Eat a normal, balanced diet. Foods which have high numbers of vitamin K (eg, leafy green vegetables, broccoli, liver, certain vegetable oils) may affect the effect of Coumadin. Ask your doctor to get a listing of foods that may affect Coumadin. Tell your medical professional if any foods listed really are a part of your diet plan.
• Do not eat cranberry products or drink cranberry juice while you take Coumadin. Tell a medical expert if these items happen to be a part of what you eat.
• Elevated body's temperature may improve the effect of Coumadin. Be careful to avoid becoming overheated, especially during summer.
• Coumadin decreases blood clotting. Use caution while doing activities such as brushing your teeth, flossing, or shaving. Avoid activities that may cause bruising or injury. Seek immediate medical attention if you fall or injure yourself. Tell your doctor if you have unusual bruising or bleeding. Tell a medical expert if you have dark, tarry, or bloody stools.
• Do not take aspirin whilst you take Coumadin unless a medical expert tells you to. If you already take aspirin to get a heart or any other condition, talk with a medical expert about whether or not you should preserve to take it with Coumadin.
• Tell a medical expert in case you will probably be traveling or in case you will be confined to a bed or chair for the long time period of time (eg, car or airplane ride). This may raise your chance of developing a blood clot.
• If therapy with Coumadin is stopped, the blood thinning effects will last for 2 to 5 days after you stop taking it. Discuss any queries or concerns with your medical professional. Do not suddenly stop taking Coumadin without checking with your doctor.
• Lab tests, including certain blood clotting tests (eg, PT, INR), could be performed whilst you use Coumadin. These tests could be utilized to monitor your complaint or search for side effects. Be sure to keep all doctor and lab appointments.
• Use Coumadin with caution in Asian patients; they may be more understanding of its effects, especially bleeding.
• Use Coumadin with caution inside the elderly; they could be more responsive to its effects, especially bleeding.
• Coumadin should be combined with extreme caution in kids; safety and effectiveness in children haven't been confirmed. Children may require more frequent tests if they use Coumadin.
• If you can be pregnant, you should work with an effective type of contraception when you take Coumadin. If you might have questions on effective birth control, talk with your doctor.
• Pregnancy and breast-feeding: Do not use Coumadin if you are pregnant. It has been shown to cause harm to the fetus. Avoid becoming pregnant when you take it. If you think you could possibly be pregnant, contact your doctor immediately. It is not known if Coumadin is located in breast milk. If you are or is going to be breast-feeding while you use Coumadin, seek advice from your medical professional. Discuss any possible risks for your baby.