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Promethazine is within a group of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing those things of chemicals inside your brain. Promethazine also acts as an antihistamine. It blocks the results with the natural chemical histamine in your body.

Promethazine is employed to deal with allergic reactions including itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Promethazine also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used as a sedative or sleep aid.

Promethazine just isn't to be used for symptoms of asthma, pneumonia, or another lower respiratory tract infections.


Take promethazine exactly as prescribed from your doctor. Do not take it in larger amounts or over recommended. Follow the directions on your own prescription label.

Your doctor may occasionally improve your dose to make sure you receive the best results from medicines.

Promethazine might be taken with or without food or milk.

Measure liquid medicine using a marked measuring spoon or medicine cup, not having a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Call your medical professional if the symptoms do not improve, or if they get worse while taking promethazine.

This medication may cause one to have unusual results with certain lab tests. Tell any doctor who treats you that you are using promethazine.

Seek emergency medical help if you think maybe you've used an excessive amount this medicine. Overdose symptoms can include severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting.


Take it as being prescribed from your doctor.


Store promethazine at room temperature from moisture, heat, and light-weight.


Active Ingredient: Promethazine



Side Effects

Get emergency medical help if you have all of these signs of an allergic reaction: hives; breathlessness; swelling of your respective face, lips, tongue, or throat. Stop using promethazine and call a medical expert immediately if you've any of these serious side effects:

twitching, or uncontrollable movements of the eyes, lips, tongue, face, arms, or legs;

tremor (uncontrolled shaking), drooling, trouble swallowing, difficulty with balance or walking;

feeling restless, jittery, or agitated;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;

feeling like you might distribute;

seizure (convulsions);

pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms;

decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;

hallucinations, agitation;

nausea and stomach pain, skin rash, and jaundice (yellowing in the skin or eyes);

urinating lower than usual or otherwise not in any respect;

joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color; or

slow heartbeat, weak pulse, fainting, slow breathing (breathing may stop).

Less serious promethazine unwanted side effects can sometimes include:

dizziness, drowsiness, anxiety;

blurred vision, dry mouth, stuffy nose;

ringing inside your ears;

weight gain, swelling within your hands or feet;

impotence, trouble using an orgasm; or


This isn't a complete report on unwanted side effects while others may occur. Tell your doctor about any unusual or bothersome side-effect.


Stop using promethazine and call your doctor simultaneously if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early signs and symptoms of dangerous unwanted side effects. Promethazine can cause unwanted effects that may impair your thinking or reactions. Be careful in case you drive or do anything whatsoever that will need one to be awake and alert. Avoid having a drink, which may increase some in the unwanted side effects of promethazine. There are many other medicines that could communicate with promethazine. Tell a medical expert about all of the prescription and over-the-counter medications you utilize. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your medical professional. Keep a list together with you of each of the medicines you employ and show this list to any doctor or other doctor who treats you.

Important safety information:

Promethazine should not be presented to a child younger than 24 months old. Promethazine can cause severe breathing problems or death in a child younger than 2. Carefully follow your physician's instructions when giving this medicine to a youngster of any age. Do not use medicines if you have severe asthma, emphysema, and other breathing problem, or should you are allergic to promethazine or other phenothiazines for example chlorpromazine (Thorazine), fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), thioridazine (Mellaril), or trifluoperazine (Stelazine).

If you've got certain conditions, you may need a dose adjustment or special tests to soundly use prescription drugs. Before you take promethazine, tell your doctor if you might have:

a history of seizures;

heart disease or hypertension;

liver or kidney disease;

severe asthma, emphysema, chronic obstructive pulmonary disease (COPD) or another breathing problem;

sleep apnea (breathing stops throughout sleep);


a stomach ulcer or digestive obstruction;

bone marrow depression;

adrenal gland tumor (pheochromocytoma);

enlarged prostate or problems with urination;

low numbers of calcium in your blood (hypocalcemia); or

if you've got ever had a serious side effect while using promethazine or any other phenothiazine.

FDA pregnancy category C. It is not known whether promethazine is harmful to an developing fetus. Tell a medical expert should you are pregnant or want to conceive during treatment. It just isn't known whether promethazine passes into breast milk or if it might harm a nursing baby. Do not use prescription drugs without telling your doctor in the event you are breast-feeding an infant. Older adults may be very likely to have unwanted effects from promethazine.

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