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Micronase (Glyburide) is surely an oral diabetes medicine which enables control blood sugar.

Glyburide is employed to treat diabetes type 2.

This drugs are not for treating type 1 diabetes.

Glyburide could also be used for other purposes unlisted in this medication guide.


Take exactly as prescribed through your doctor. Do not take in larger or smaller amounts or for more than recommended. Follow the directions on your own prescription label. Your doctor may occasionally change your dose to ensure that you receive the best results.

Take glyburide using your first meal through the day, unless your medical professional notifys you otherwise.

Your blood sugar levels should be checked often, and you might need other blood tests at a medical expert's office. Visit your doctor regularly.
Know the signs and symptoms of low blood glucose levels (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a way to obtain sugar obtainable in case you have signs of low blood glucose. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and can't eat or drink, work with an injection of glucagon. Your doctor can provide you with a prescription to get a glucagon emergency injection kit and let you know the best way to provide the injection.

Also watch for signs of blood glucose which is too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

Check your blood glucose carefully during a time of stress or illness, in case you travel, exercise more than usual, drink alcohol, or skip meals. These things may affect your sugar levels and your dose needs may also change.

Your doctor might want you to definitely stop taking glyburide to get a short period of time in the event you get ill, have a very fever or infection, or if you've got surgical treatment or a medical emergency.
Ask a medical expert the way to adjust your glyburide dose as required. Do not alter your medication dose or schedule without your doctor's advice.

If there are any modifications in the manufacturer, strength, or form of glyburide you utilize, your dosage needs may change. Always check your refills to ensure that you have received the correct logo and sort of medicine prescribed by your doctor.


Take as prescribed from your doctor.


Store at room temperature, protected against moisture, heat, and lightweight.


Active ingredient: Glyburide

Side Effects

Stop using glyburide and get emergency medical help if you've these warning signs of a hypersensitive reaction: hives; difficulty breathing; swelling of one's face, lips, tongue, or throat. Stop taking this medication and call your doctor simultaneously if you have some of these serious unwanted effects:

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the epidermis or eyes);

pale skin, confusion or weakness;

easy bruising or bleeding, purple or red pinpoint spots through your skin; or

headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious side effects might include:

mild nausea, heartburn, feeling full;

joint or muscle pain;

blurred vision; or

mild itching or skin rash.

This is not a complete set of unwanted effects while others may occur. Call a medical expert for medical advice about negative effects.


You should not use this medication should you are allergic to glyburide, or:

if you are receiving care with bosentan (Tracleer);

if you've type 1 diabetes; or

should you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

To make sure you can safely take glyburide, tell a medical expert if you've got these other conditions:

hemolytic anemia (a lack of red blood cells);

an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

a nerve disorder affecting bodily functions;

liver or kidney disease;

if you are allergic to sulfa drugs; or

if you've been using insulin or taking chlorpropamide (Diabinese).

Certain oral diabetes medications may improve your risk of serious cardiovascular disease. However, not treating your diabetes may damage your heart and also other organs. Talk to a medical expert in regards to the risks and benefits of handling your diabetes with glyburide.

FDA pregnancy category C. It is not known whether glyburide will harm an baby. Similar diabetes medications have caused severe hypoglycemia in babies whose mothers had used the medication near the period of delivery. Tell your medical professional should you are pregnant or plan to become pregnant with all the medicines. It is not known whether glyburide passes into breast milk or if it could possibly harm a nursing baby.

Do not use medicines without telling your physician in case you are breast-feeding a baby. Older adults may be prone to have low blood glucose while taking glyburide.


Important safety information:

You should avoid using medicines in the event you are allergic to glyburide, if you are undergoing treatment with bosentan (Tracleer), if you have type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call a medical expert for treatment with insulin).

Before taking glyburide, tell a medical expert if you are allergic to sulfa drugs, if you've got been using insulin or chlorpropamide (Diabinese), or if you have hemolytic anemia (a lack of red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease.

Take care to never let your blood glucose levels get too low. Low blood sugar levels (hypoglycemia) can take place in case you skip lunch, exercise too much time, consume alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets along with you in case you've low blood sugar. Other sugar sources include orange juice and milk. Be sure your loved ones and good friends know the way to direct you towards an unexpected emergency.

Drug interactions

Tell your doctor about all the medications you utilize, especially:

a blood thinner for example warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

disopyramide (Norpace);

fluconazole (Diflucan), ketoconazole (Nizoral);

fluoxetine (Prozac);

rifampin (Rifadin, Rimactane, Rifater);

an ACE inhibitor such as enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), while others; or

an antibiotic including ciprofloxacin (Cipro), levofloxacin (Levaquin), while others.

Using certain medicines causes it to be harder for that you tell when you've got low blood glucose levels. Tell your physician in case you use the following:

albuterol (Proventil, Ventolin);

clonidine (Catapres);

reserpine; or

beta-blockers for example atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), yet others.

You could possibly be prone to have hyperglycemia (high blood glucose levels) if you take glyburide with:


diuretics (water pills);

steroids (prednisone yet others);

phenothiazines (Compazine and others);

thyroid medicine (Synthroid and others);

birth control pills along with other hormones;

heart or blood pressure level medications (Cartia, Cardizem, Nifedical, Covera, Verelan, and others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, among others);

seizure medicines (Dilantin among others); and

diet pills or medicines to treat asthma, colds or allergies.

You might be more prone to have hypoglycemia (low blood sugar) in the event you take glyburide with:

clarithromycin (Biaxin);

exenatide (Byetta);

probenecid (Benemid);

heart or blood pressure level medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, yet others);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin and other salicylates (including Pepto-Bismol);

sulfa drugs (Bactrim, Gantanol, Septra, while others);

a monoamine oxidase inhibitor (MAOI); and

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

These lists are certainly not complete and you will find many other medicines that may increase or decrease the effects of glyburide on reducing your blood glucose levels. Tell your medical professional about all medications you utilize. This includes prescription, over-the-counter, vitamin, and herbal products. Do not find a new medication without telling your medical professional.


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