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Mestinon (Pyridostigmine) affects chemicals in your body which are involved in the communication between nerve impulses and muscle movement.

Pyridostigmine is used to treat the signs and symptoms of myasthenia gravis. It is also found in military personnel who are exposed to nerve gas.

Pyridostigmine may also be used for purposes not listed on this medication guide.


Take just as prescribed through your doctor. Do not take in larger or smaller amounts and for more than recommended. Follow the directions on the prescription label.
Take this medicine with food or milk when it upsets your stomach. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking or opening the pill may cause a lot of drug to be removed in the past.

Measure liquid medicine using a special dose measuring spoon or medicine cup, not with a regular table spoon. If you do not have a very dose measuring device, ask your friendly phamacist first.

The amount and timing with this drugs are essential to the success of your respective treatment. Carefully follow your doctor's instructions about how precisely much medicine to consider and when to take it.

Your doctor may occasionally improve your dose to ensure that you receive the best results. You may be motivated to keep a daily record of once you took each dose and just how long the results lasted. This will help your physician decide if your dose needs to be adjusted.
If you need surgery, tell the surgeon beforehand that you will be using pyridostigmine. You may need to stop with all the medicine for the short time. Store at room temperature away from moisture and warmth.


Take the medicine as prescribed through your doctor.


Keep the tablets inside their original container, with the canister of moisture-absorbing preservative that comes with this medicine.


Active ingredient: Pyridostigmine

Side Effects

Get emergency medical help for those who have some of these signs of an allergic reaction: hives; lack of breath; swelling of your face, lips, tongue, or throat. Stop using pyridostigmine and call your doctor at once for those who have any of these serious unwanted effects:

extreme muscle weakness, muscle twicthing;

slurred speech, vision problems;

severe vomiting or diarrhea;

cough with mucus;

confusion, anxiety, panic disorder;

seizure (convulsions); or

worsening or no improvement inside your signs of myasthenia gravis.

Less serious unwanted side effects might include:

cold sweat, pale skin;

urinating more than usual;

watery eyes;

mild nausea, vomiting, or upset stomach;

warmth or tingly feeling; or

mild rash or itching.

This just isn't a complete list of unwanted effects and others may occur. Call your medical professional for health advice about unwanted effects.


You should avoid using pyridostigmine should you be allergic into it, or if you have a very bladder or bowel obstruction.

To be sure to can safely take pyridostigmine, tell a medical expert for those who have some of these other difficulties:


kidney disease;

an ulcer or other serious stomach disorder;

high hypertension, heart disease;

overactive thyroid; or

a history of seizures.

It isn't known whether pyridostigmine will harm an baby. Tell a medical expert if you are pregnant or intend to conceive with all the prescription drugs. It is just not known whether pyridostigmine passes into breast milk or whether or not this could harm a nursing baby. Do not use this medication without telling your physician if you are breast-feeding an infant.

Drugs interaction 

Tell your doctor about all the medicines you use, especially:

atropine (Atreza, Sal-Tropine);

belladonna (Donnatal, among others);

benztropine (Cogentin);

clidinium (Quarzan);

clozapine (Clozaril, FazaClo);

dimenhydrinate (Dramamine);

methscopolamine (Pamine), scopolamine (Transderm Scop);

glycopyrrolate (Robinul);

mepenzolate (Cantil);

bladder or urinary medications including darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

bronchodilators for example ipratropium (Atrovent) or tiotropium (Spiriva);

cold medicine, allergy medicine, or sleeping pills that contain an antihistamine including diphenhydramine (Tylenol PM) or doxylamine (Unisom);

heart rhythm medication such as quinidine (Quin-G), procainamide (Procan, Pronestyl), disopyramide (Norpace), flecaininde (Tambocor), mexiletine (Mexitil), propafenone, (Rythmol), yet others;

irritable bowel medications for example dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine);

medicine to treat Alzheimer's dementia, such as donepezil (Aricept), rivastigmine (Exelon), or tacrine (Cognex); or

a steroid like betamethasone (Celestone) or dexamethasone (Cortastat, Dexasone, Solurex, DexPak).

This list just isn't complete and other drugs may communicate with pyridostigmine. Tell your physician about all medications you utilize. This includes prescription, over-the-counter, vitamin, and herbal products. Do not find a new medication without telling your doctor.

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